KEYNOTE-905: perioperative enfortumab vedotin and pembrolizumab in MIBC

Christof Vulsteke, MD, PhD, AZ Maria Middelares, Ghent, Belgium, discusses results from the Phase III KEYNOTE-905 study (NCT03924895) evaluating perioperative enfortumab vedotin plus pembrolizumab in patients with muscle-invasive bladder cancer (MIBC) who were ineligible for cisplatin. Clinically meaningful improvements in event-free survival, overall survival, and pathological complete response rates were observed. Safety was manageable and consistent with known profiles. This interview took place at 2025 European Society for Medical Oncology (ESMO) Asia Congress in Singapore, Singapore. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

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