Virology Lectures 2020 #6: RNA directed RNA synthesis
RNA virus genomes are copied into mRNA by a viral enzyme, RNA dependent RNA polymerase, which has no counterpart in the cell. In this lecture we discuss the principles and mechanisms of RNA synthesis by these enzymes, including priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and the switch from synthesis of mRNAs to genomes.
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