Ação do GABA e dos benzodiazepínicos - DIAZEPAM

GABA is an inhibitory neurotransmitter. It is widely distributed in the brain and spinal cord. We find two GABA receptors: An ionotropic GABA A receptor A metabotropic GABA B receptor The importance of inhibitory neurotransmitters lies in the fact that neurons are extensively interconnected. Without the activity of inhibitory synapses, these interconnections could destabilize the brain. An inhibitory influence is exerted by neurons that secrete GABA, which are present in large numbers in the brain. One site of the GABA A receptor binds to a class of tranquilizing drugs called BENZODIAZEPINES: Diazepam Valium Clonazepam