Hereditary Hyperbilirubinemia Syndromes

This video discusses hereditary disorders associated with bilirubin conjugation defects (e.g., Gilbert’s Syndrome, Crigler-Najjar Syndrome) and bilirubin excretion defects (e.g., Dubin-Johnson Syndrome, Rotor Syndrome) in addition to non-hereditary disorders with similar presentations (e.g., physiologic neonatal jaundice, biliary atresia). This individual GI lecture video has been clipped directly from the comprehensive GI lecture series videos and may therefore contain errors associated with this process. You can find the “GI Lecture Series” playlist on the channel to watch the full lecture videos in their entirety. Studying for board examinations can be daunting, with every resource offering a unique take on each medical condition. I created this channel to provide medical students - especially those studying for USMLE Step 1 and COMLEX Level 1 - with a "one-stop-shop" for medical content. For each lecture, I synthesized information from almost every major medical resource to provide you with a comprehensive and integrated lesson plan. I emphasize the pathophysiology of each disease so that you can leave each lecture with a detailed understanding of the material instead of memorizing hundreds of random facts. All content discussed within the lecture series is designed for educational purposes only and should not substitute clinical judgment. Original material in this lecture series may be redistributed provided that proper attribution is utilized. Please use “   / @doc.smoove”   when attributing source material. Errata: Timestamps: 0:00 Overview 1:12 Gilbert’s Syndrome 3:40 Crigler-Najjar Syndrome 4:38 Kernicterus 7:27 Crigler-Najjar Syndrome (Cont.) 8:58 Physiologic Neonatal Jaundice 11:40 Dubin-Johnson Syndrome 14:28 Rotor Syndrome 15:04 Biliary Atresia