Longevity Scientist: Can This Supplement Really Reverse Aging?

Feeling tired, foggy, or weaker as you age? The problem might not be your age itself, but the health of your cellular powerhouses: the mitochondria. When your mitochondria decline, your energy plummets, inflammation rises, and the aging process accelerates, becoming the root cause of nearly every chronic disease. In this episode, I speak with leading immunologist and mitochondrial longevity scientist, Dr. Anurag Singh, about the breakthrough research on a powerful postbiotic called Urolithin A. This unique compound, derived from pomegranates and nuts but which only 10% of Americans can naturally produce, helps your body clear out old, damaged "zombie" mitochondria and build new, healthy ones—a process called mitophagy. Dr. Singh reveals stunning clinical data showing how supplementing with Urolithin A (Mitopure) can increase strength by 12% and cardiovascular fitness (VO2 max) by 10%—without any changes to diet or exercise. We also uncover the common lifestyle factors and medications (like statins) that act as mitochondrial toxins and discuss a complete, science-backed toolkit to protect and rejuvenate your cellular energy for a long, healthy life. You’ll learn: • Why your mitochondria impact energy, metabolism, and how you age • The role Urolithin A supports cellular renewal—and what that means for your strength • How you can pair fasting, movement, and nutrients for better energy and recovery • Why personalized strategies can support your energy, focus, and strength over time This episode is packed with takeaways for boosting your cellular energy—and it’s one of the most practical conversations I’ve had on the science of longevity. #Longevity #Mitochondria #ReverseAging #UrolithinA #DrMarkHyman #podcast #functionalmedicine View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_c... Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?u... Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Pique, BON CHARGE, Paleovalley and Timeline. Visit https://seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Head to https://piquelife.com/hyman to get 20% off + a free beaker and frother today. Go to https://boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Get nutrient-dense, whole foods. Head to https://paleovalley.com/hyman for 15% off your first purchase. Support essential mitochondrial health and save 20% on Mitopure. Visit https://timeline.com/drhyman to get 20% off today. (0:00) Introduction to Mitochondrial Health and Its Importance (2:02) Innovations and Strategies for Optimizing Mitochondrial Function (5:20) Recognizing Symptoms and Diseases Linked to Mitochondrial Dysfunction (7:39) How to Diagnose Mitochondrial Issues (10:03) VO2 Max Testing and Longevity (13:28) Mitochondrial Health and Its Relationship with Inflammation (15:08) Exploring Causes and Solutions for Mitochondrial Dysfunction (21:06) Sleep, Toxins, and the Microbiome's Impact on Mitochondria (25:14) Diet, Exercise, and Supplements in Supporting Mitochondria (27:10) Muscle Health and Mitochondrial Function in Aging (29:15) Natural Ways to Promote Mitochondrial Renewal (32:38) Nutrients and Diet for Mitochondrial and Muscle Health (37:20) Urolithin A Discovery and Its Effects on Mitochondria (43:27) Long-term Benefits of Urolithin A and Its Role in Chronic Diseases (50:17) Urolithin A's Potential in Cancer Recovery and Immune Health (53:43) Cardiovascular and Skin Health Benefits of Urolithin A (56:50) The Future of Mitochondrial Research and Practical Applications (1:03:09) Advances in Brain Health and Diagnostic Tools for Mitochondria (1:05:02) Statins, Steroids, and Drugs Affecting Mitochondrial Health (1:07:34) Holistic Strategies and Exciting Research in Mitochondrial Function (1:13:32) Emphasizing Longevity and the Importance of Early Intervention (1:13:49) Closing Remarks