5. Library Complexity and Short Read Alignment (Mapping)

MIT 7.91J Foundations of Computational and Systems Biology, Spring 2014 View the complete course: http://ocw.mit.edu/7-91JS14 Instructor: David Gifford Prof. Gifford talks about library complexity as it relates to genome sequencing. He explains how to create a full-text minute-size (FM) index, which involves a Burrows-Wheeler transform (BWT). He ends with how to deal with the problem of mismatching. License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses at http://ocw.mit.edu