Can You Beat Isaac if You HAVE TO Clear a Room Every 30 Seconds?

Streamed LIVE ►   / anothermatt_   EDITED by Pupzel ► https://x.com/PupzelPup -------------------------------------------------------------------- MERCH ► https://www.redbubble.com/people/Anot... Discord ►   / discord   Twitter ►   / another_matt   -------------------------------------------------------------------- Channel Art ► GrumpyTogepi:   / grumpytogepi   -------------------------------------------------------------------- The Binding of Isaac Repentance, Repentance PLUS +, Rebirth, Afterbirth, Afterbirth+, whatever else there is is meant to be played one way. I did it the opposite way i'm pretty sure. Anyways no polyphemous, C Section, Brimstone, Mom's Knife, Haemolacrea crazy broken build run here. Only Isaac and his mad hops #bindingofisaac #gaming #challenge