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#Teeth #Regeneration #Infinite #Cultivation #New Technology Dental News TV previously reported on a Japanese research team's tooth regeneration efforts. Dental research teams around the world are accelerating their research to find a way to grow "true biological teeth" in the human jaw, reaching a new turning point. Instead of conventional implants and crowns, the possibility of real teeth grown from a patient's own cells is increasing. Professor Ana Angelova Volponi's research team at King's College London has successfully cultivated dental organoids, or models of dental tissue, using a combination of human and mouse cells. This year's research developed a hydrogel that can replace conventional collagen scaffolds, creating a laboratory environment similar to that of a real mouth. The advantages of this technology are clear. Biological teeth grown from the patient's own cells can be implanted without immune rejection, maintaining sensation and elasticity, just like real teeth. This is a significant difference compared to conventional implants, which are firmly anchored to bone but lack sensation. Professor Volponi stated that complete replacement with human cells is not yet possible, but he proposed two approaches. Some involve partially growing teeth in the laboratory and then implanting them in the alveolar socket, allowing them to grow naturally. Others involve surgically transplanting fully grown teeth. Related research is also underway around the world. A research team in Osaka, Japan, is conducting clinical trials of an antibody-based treatment for patients with congenital adonitis, and researchers at Tufts University in the United States have combined human and pig cells to regenerate human-like teeth in pig mouths. A research team at the University of Washington is also attempting to replicate the human tooth formation process in the laboratory by culturing dental pulp stem cells using stem cells extracted from wisdom teeth. Experts predict that this research will go beyond mere experiments and that biological tooth restoration and replacement could become a reality within the next decade. The era of restoring lost teeth to resemble natural teeth is expected to be upon us in the near future.