Insulin Resistance Explained: Early Metabolic Disease & How to Reverse It

What does it mean to be insulin resistant? How does it happen and what can you do about it? Dr David Samra (MD, FACSEP) is a Specialist Sport and Exercise Medicine Physician and Founder of Progressive Sports Medicine and Progressive Longevity Clinic in Sydney, Australia Insulin resistance is one of the earliest and most important drivers of metabolic disease — often developing years before diabetes, fatty liver, or cardiovascular disease become clinically apparent. In this lecture, Dr Samra explains what insulin resistance actually is at a physiological level, how it develops, and why it matters for long-term health, performance, and ageing. Topics include: • Early metabolic dysfunction and hyperinsulinaemia • The role of muscle, liver, and visceral fat • Why normal blood glucose can be misleading • The link to cardiovascular disease, fatty liver, and inflammation • Evidence-based strategies to improve insulin sensitivity This is not about weight alone — it’s about understanding and addressing the biology that underpins modern chronic disease. Recommended viewing for the Progressive Longevity Clinic Education Series. 📍 Progressive Longevity Clinic, Sydney, Australia 📞 (02) 8540 8019 🌐 www.progressivespecialists.com.au 📷 Instagram: @progressivesportsmed 🔗 LinkedIn: www.linkedin.com/in/david-samra-psm Disclaimer: This content is for educational purposes only and does not constitute medical advice. Please consult your GP or specialist for individual assessment and care.