Unpacking Rare Lung Diseases: Alpha-1 Antitrypsin Deficiency 1/3: Understanding Alpha-1

In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care. James Stoller, Chief of Education, Pulmonary Physician, Cleveland Clinic; Professor of Medicine and Senior Associate Dean, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Ohio, USA Stoller’s work spans clinical care, medical education, and leadership development. He is a nationally and internationally recognised expert in alpha-1 antitrypsin deficiency (AATD), and has played a central role in shaping how this rare condition is diagnosed and managed.