Comprendre la maladie de Parkinson : mécanismes, symptômes, recherche | CHU de Bordeaux et Mollat

Understanding Parkinson's to Better Combat It: When Science Mobilizes for the Brain This conference, broadcast on the Bordeaux University Hospital (CHU) channel in partnership with the Mollat ​​bookstore, brings together Dr. Alexandra Foubert-Samier, neurologist and coordinator of the Bordeaux University Hospital's Parkinson's Expert Center, and Gaëlle Brothier, nurse coordinator at the same center. They shed light on Parkinson's disease, its mechanisms, and current research advances. Parkinson's disease affects millions of people and is the second leading cause of motor disability in seniors. Often associated with tremors, it is actually much more complex and encompasses a wide variety of forms. This progressive neurological disorder is linked to the gradual loss of dopaminergic neurons in the brain. Program: • Risk factors: age, genetics, pesticides • Brain mechanism: central role of dopamine • Motor and non-motor symptoms (sleep, cognitive impairment, dysautonomia) • Impacts on daily life and quality of life • Drug treatments and therapeutic strategies • Advanced therapies: pumps, neurostimulation • Non-drug approaches and support • Current research: gene therapy, stem cells, immunotherapy • Prospects and hope for a future curative treatment Chapters 00:00 Introduction and key figures in France 02:45 Risk factors: age, genetics, and pesticides 03:45 Brain mechanism: the role of dopamine 05:44 Motor symptoms: beyond tremor 07:16 The iceberg of non-motor and sleep disorders 09:44 Dysautonomia: digestion, tension, and swallowing 12:09 Cognitive and psycho-behavioral impacts 13:37 Drug Treatments and Therapeutic Classes 15:38 Disease Progression and Motor Fluctuations 17:28 Second-Line Therapies: Pumps and Neurostimulation 20:30 Importance of Non-Drug Approaches 23:02 Differential Diagnoses and Related Diseases 24:39 Research: Gene Therapy and Stem Cells 36:21 Future Directions: Immunotherapy and French Trials 45:21 Resilience Models: The Example of Michael J. Fox Find information from Bordeaux University Hospital and the Parkinson's Expert Center: https://www.chu-bordeaux.fr/ Mollat ​​Evening Information: https://www.chu-bordeaux.fr/Espace-m%... Parkinson Expert Center Information: https://www.chu-bordeaux.fr/Les-unit%... Music: © Mollat Subtitles automatically generated in French by YouTube.