HIRN Webinar: Circulating Extracellular Vesicles in Type One Diabetes (T1D)

Thursday, October 24, 2024 Presentations by: Raghu Mirmira, MD, PhD, University of Chicago Ernesto Nakayasu, PhD, Pacific Northwest National Laboratory Emily Sims, MD, Indiana University School of Medicine Topics discussed: A highly sensitive proteomics platform enables extracellular vesicle (EV) analysis from minimal plasma volumes. Proteomics analysis of auto-antibody positive plasma identifies potential biomarkers. Beta cell EVs carrying PD-L1 reduce CD8 T cell activation. Plasma EV PD-L1 cargo correlates with residual C-peptide in AAb+ individuals and in individuals with new-onset T1D

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