The Changing Face of Liver Transplantation: ALD, MASLD, and the Growing Wait List

Dr. Neil D Shah, Transplant Hepatology Program Director at UNC Chapel Hill and Chair of the National Liver Review Board, examines how the epidemiology of liver disease is reshaping transplantation in the United States. In this lecture, Dr. Shah reviews: Current U.S. wait list dynamics (~8,600 active candidates, ~12,000 annual transplants) The decline of HCV and reciprocal rise in alcohol-associated liver disease (ALD) Early liver transplantation for severe alcohol-associated hepatitis Equity barriers in ALD transplantation The projected MASLD burden through 2050 Expanding oncologic indications: HCC beyond Milan, colorectal liver metastases, and intrahepatic cholangiocarcinoma Acute-on-chronic liver failure (ACLF-3) and waitlist mortality Essential viewing for transplant hepatologists, gastroenterologists, and trainees navigating modern allocation. 👉 Visit https://www.inedsys.com for the complete video. Disclaimer: Views expressed are those of Dr. Shah and do not reflect the OPTN.