CJC-1295, Ipamorelin, Tesamorelin & Sermorelin: Deep Dive on the Best GH Peptides
Growth hormone peptides like CJC-1295, Ipamorelin, Tesamorelin, and Sermorelin are some of the most popular compounds in longevity and performance medicine—but most people using them are asking the wrong question. They want to know which peptide increases GH the most. But more GH isn't always better, and the way you increase it matters just as much as how high you drive it. In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the full science behind GH peptides: how growth hormone actually works, why CJC-1295 with DAC disrupts normal physiology, what the clinical data on Tesamorelin and Sermorelin actually shows, why Ipamorelin is the only GHRP worth recommending for most people, and how to weigh the real benefits of these peptides against their real risks—including insulin resistance, cancer progression, and potential lifespan tradeoffs. This isn't Reddit dosing lore. This is the evidence-based deep dive. 💥 Whether you're exploring GH peptides for body composition, visceral fat loss, recovery, or longevity—this is the most thorough breakdown of CJC-1295, Ipamorelin, Tesamorelin, Sermorelin, and MK-677 you'll find. 🔬 In this video, you'll learn: ✅ How growth hormone actually works—and why increasing it isn't always anti-aging ✅ The real benefits of GH and IGF-1 (and the downsides most content ignores) ✅ Normal GH physiology and why pulsatility matters ✅ CJC-1295 with DAC vs without DAC—and why this distinction changes everything ✅ Sermorelin vs Tesamorelin vs CJC-1295 (no DAC): half-lives, potency, and clinical data compared ✅ Why CJC-1295 with DAC raises trough GH 7.5-fold and why that's a problem ✅ The only human clinical data we actually have—and what's missing ✅ GHRP deep dive: GHRP-6, GHRP-2, Hexarelin, Ipamorelin & MK-677 compared ✅ Why Ipamorelin is the only selective GHRP and what that means practically ✅ Why GHRP monotherapy likely won't raise IGF-1 long-term ✅ The synergistic effect of combining a GHRH + GHRP—and the human data behind it ✅ How to decide which GHRH analogue is right for you based on your health profile ✅ Who should and shouldn't consider GH peptides at all 🎯 Best for: – Anyone researching CJC-1295, Ipamorelin, Tesamorelin, or Sermorelin – Individuals exploring GH peptides for fat loss, muscle gain, or recovery – Longevity-focused individuals who want the tradeoffs, not just the benefits – Clinicians and practitioners exploring peptide-based therapies – Biohackers wanting an evidence-based breakdown that goes beyond community protocols – Anyone who's heard conflicting things about CJC-1295 with vs without DAC 📍 Timestamps 00:00 Are You Using the Wrong GH Peptides? 01:26 Benefits of Increasing GH and IGF-1 04:17 Downsides of Increasing GH and IGF-1 07:45 GH Replacement with Aging vs Using GH Peptides 10:18 Normal Growth Hormone Physiology (GH, Ghrelin, Somatostatin, IGF-1) 14:38 How the Different GH Peptides Act on the GH Pathway 15:49 GHRH Analogue Structures - CJC-1295 vs Sermorelin vs Tesamorelin 17:59 Half-Lives of CJC-1295 Without DAC vs Sermorelin vs Tesamorelin 20:00 Negatives of CJC-1295 With DAC Compared to Without DAC 23:45 Potency of CJC-1295 vs Sermorelin vs Tesamorelin 25:51 Sermorelin Human Studies Review 28:17 Tesamorelin Human Studies Review 32:18 CJC-1295 With and Without DAC Human Studies Review 34:50 Costs of CJC-1295 vs Tesamorelin vs Sermorelin 35:29 When to Use (or Not Use) CJC-1295 With DAC 38:15 When to Use CJC-1295 Without DAC vs Tesamorelin vs Sermorelin 46:20 GHRP’s and Ghrelin - How to Differentiate by Selectivity, Potency, & Half-Life 48:19 GHRP Overview - Ipamorelin vs Ghrelin vs GHRP-6 vs GHRP-2 vs Hexarelin 52:51 MK-677 - Oral Route, Long Half Life, Human Data, and vs Ipamorelin 57:53 Why You Should Not Use a GHRP Alone (Desensitization) 01:00:44 Synergy of a GHRH + GHRP (i.e. CJC-1295 and Ipamorelin Together) 01:02:52 When Should You Add in Ipamorelin to Your GH Peptide Stack? 01:04:22 Should YOU Use GH Peptides At All? 01:05:18 Benefits of GH Peptides 01:08:00 Risks of GH Peptides ▶️ Related Video Top 5 Peptides for Longevity → • Top 5 Peptides for Longevity – Medical Doc... Subscribe for more: Weekly videos on peptides, longevity & performance 🔔 Next: GH Peptides Part 2 — Dose, Timing, Frequency & Cycles ⚠️ Medical Disclaimer This video is for educational and informational purposes only and does not constitute medical advice. Other than Tesamorelin, GH peptides are not approved by the FDA for human use and are sold for research purposes only. Their safety and effectiveness have not been established in human clinical trials, and long-term risks are unknown. Do not use this information to diagnose or treat any medical condition. Always consult a qualified healthcare provider before making any medical decisions. #CJC1295 #Ipamorelin #GHPeptides #Peptides #Longevity

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