The COSY NMR experiment - Who is your neighbor? | nmr.academy

Beginner NMR course for students available at https://nmracademy.thinkific.com/courses/n... COSY (Correlation Spectroscopy) is a two-dimensional Nuclear Magnetic Resonance (NMR) technique that is used to study the correlations between hydrogen atoms in a molecule. It provides detailed information about the connectivity of protons in a molecule, revealing the number of neighboring protons and their chemical shift values. The technique is extremely useful, when there is extensive signal overlap in the one-dimensional spectrum. More about COSY (with some nice eamples) in the video. What information COSY provides 0:00 The COSY pulse sequence 1:52 Example 1: Ethyl acetate 3:48 Example 2: Ethyl propionate 6:14 Example 3: 4-hydroxybutanal 8:13