PCD expert talks: Measuring nasal nitric oxide in children

Early Career Researchers in PCD Expert Talk by Dr Nicole Beydon and Prof Jane Lucas 25.05.2023. Measuring nasal nitric oxide is an important component of diagnostic testing for primary ciliary dyskinesia. Anyone taking any physiological measurement should ideally follow a standardised method, so that results are comparable between different centres. Until recently there was no international standard for measuring nasal nitric oxide in young children.   First we will present results of a global survey which demonstrated considerable variability of equipment, measurement methods and reporting. We will then discuss the recently published ERS Standards for measuring PCD in children which aims to address this problem. Our talk will be practical, with lots of examples to help you measure, interpret and report nasal nitric oxide in accordance with the ERS Standard; we’ll consider different aged children, and the commonly available analysers. We’ll aim to keep the session interactive with plenty of time for questions. About the speakers: Nicole Beydon and Jane Lucas led and chaired the recent ERS Task force that developed the standards for measuring nasal nitric oxide in children. Jane is Professor of Paediatric Respiratory Medicine at University of Southampton, and leads the national PCD Diagnostic service in Southampton. She also led the ERS Diagnostic Guidelines (2017) and founded and chaired BEATPCD (2014-19). Nicole is a paediatric pulmonologist involved in respiratory physiology and lung function testing for more than 10 years. She is the head of the paediatric department of Physiology-Lung function test and Sleep medicine at Armand Trousseau University Hospital in Paris. Since 2020, she is the chair of the 7.01 ERS group (Paediatric respiratory physiology & sleep).