Lecture 2 Pharmacokinetics ADME Shikha Therapy1

📚 Lecture 2: Pharmacokinetics (ADME) | General Pharmacology Welcome to Shikha Therapy by Lalit Parihar. In this lecture, we explore Pharmacokinetics, the study of what the body does to a drug. The lecture explains the complete journey of a drug through the body using the four fundamental processes of ADME: Absorption, Distribution, Metabolism, and Excretion. 🔬 Topics covered in this lecture: • Introduction to Pharmacokinetics • Concept of ADME • Drug Absorption • Factors affecting drug absorption • Mechanisms of drug absorption • Passive diffusion • Facilitated diffusion • Active transport • Endocytosis and filtration • Drug Distribution • Factors affecting drug distribution • Plasma protein binding • Blood-Brain Barrier • Drug Metabolism and Biotransformation • Phase I and Phase II reactions • CYP450 enzyme system • First-pass metabolism • Drug Excretion • Renal excretion of drugs • Glomerular filtration • Tubular secretion and reabsorption • Clinical importance of Pharmacokinetics 🎯 Learning Outcome: After completing this lecture, students will be able to understand the journey of a drug from its site of administration to its elimination from the body and explain the clinical importance of ADME in determining drug dose, route of administration, dosing interval, efficacy, and safety. This lecture is useful for students of B.Pharm, D.Pharm, Pharm.D, M.Pharm, Nursing, Medical Sciences, and students preparing for pharmacy and healthcare-related competitive examinations. 📌 Remember: Pharmacokinetics = What the body does to the drug ADME = Absorption → Distribution → Metabolism → Excretion If you find this lecture helpful, please Like, Share, Comment, and Subscribe to Shikha Therapy by Lalit Parihar for more lectures on Pharmacology, Pharmaceutical Sciences, Research Methodology, and related topics. #Pharmacokinetics #ADME #Pharmacology #DrugAbsorption #DrugDistribution #DrugMetabolism #DrugExcretion #GeneralPharmacology #BPharm #DPharm #PharmacyStudents #PharmacologyLecture #ShikhaTherapy #LalitParihar