Come vengono riparati i danni al DNA?

DNA, the fundamental code that regulates cellular life, is subject to thousands of damages every day in every cell in our body. Although these alterations can compromise genetic stability, the human body has developed sophisticated repair mechanisms to preserve the integrity of the genome. In this video, we analyze the main DNA repair processes, from the correction of base pairing errors, performed by DNA polymerase and control enzymes, to complex excision repair systems and the management of double-strand breaks. We will examine homologous recombination, which ensures accurate repair using an intact strand as a template, and non-homologous end joining, an emergency strategy that can introduce potentially dangerous mutations. We will also address the internal and external factors that cause DNA damage, such as free radicals, ultraviolet and ionizing radiation, and chemicals, and assess the impact of genetic mutations. While often associated with serious diseases, mutations play an essential role in evolution, contributing to genetic diversity and species adaptation. The video's finale focuses on the fragile balance between genetic stability and variability, a balance that underpins human health and biological evolution, and which was the subject of the previous video:    • Cosa succede quando il DNA si danneggia?   If you enjoyed this video, please leave a LIKE and subscribe to the channel so you don't miss future content 👍 OTHER RECOMMENDED VIDEOS:    • RNA e DNA: le molecole della vita      • Imparare a imparare: ecco la scienza della...      • Cosa si mangiava nel Medioevo?   You can follow me on the social media channels below to learn more and stay updated on new content:   / doc.franzonimarco     / franzoni.marco98   Where you can find me: https://linktr.ee/MarcoFranzoni 👈 Chapters: 00:00 | How is DNA damage repaired? The role of DNA polymerase 02:20 | Damage from external factors: the most serious 03:22 | Damage repair mechanisms 06:19 | What can DNA damage lead to? How is DNA damage repaired? | Marco Franzoni