Ageing Senescence | Developmental Biology | CSIR DBT JRF 2026 | Lec-37 | IFAS

Ageing Senescence explained with clear concepts and exam-focused approach. Master Ageing Senescence in Developmental Biology for CSIR NET & DBT JRF 2026 with PYQs, tricks, and problem-solving. 🔥 Join India's Best Life Science Coaching - IFAS Online! 🔥 Live Online Batch: Super Emotion Batch 7.6 - Starts on 18 May 2026 🔥 Recorded Online Batch: Revolution Batch 7.6 from Live Batch Completed on 25 April 2026 Video Timeline [00:00:00] – Introduction - Ageing Senescence | Developmental Biology [00:10:48] – Senescence & Hayflick Limit [00:12:05] – Cellular Senescence Definition [00:15:00] – Reasons: Somatic Damage [00:17:05] – Senescence Prevents Cancer [00:19:39] – Hayflick Limit (40–50 Divisions) [00:20:01] – Replicative Senescence & P53 [00:22:23] – Exceptions: Stem, Germ, Cancer Cells [00:25:24] – Causes: Telomere, ROS, Oncogenes [00:29:40] – Permanent Cell Cycle Arrest [00:30:08] – P53 Signalling Pathway [00:31:31] – P53: Arrest, Repair, Apoptosis [00:33:43] – RB & G1 Arrest [00:34:19] – Telomere Shortening Irreparable [00:35:54] – P53: Senescence vs Apoptosis [00:37:20] – Senescence Leads to Aging [00:38:38] – Aging: Physiological Deterioration [00:39:26] – Aging is Biological, Not Disease [00:40:03] – Stem Cell Pool Decline [00:44:39] – Factors: Damage & Stress [00:46:07] – Senescence/Apoptosis Promotes Aging [00:49:20] – Fast vs Slow Aging [00:53:55] – Rat vs Human Aging Example [00:55:59] – Somatic Maintenance Slows Aging [00:57:34] – Factor 1: Antioxidant-Rich Diet [01:01:05] – Factor 2: Stress Environment [01:06:00] – Factor 3: Caloric Intake & Insulin [01:08:25] – Factor 4: Mutagens & Pollution [01:09:59] – Gene: Lamin A (Progeria) [01:11:36] – Gene: Klotho (Insulin Regulator) [01:12:51] – Gene: P53 (DNA Damage Control) [01:14:25] – Gene: Sirtuins (HDAC) [01:18:05] – Gene: FOXO (Longevity) [01:19:09] – Gene: mTOR (Growth) [01:19:25] – Gene: IGF-1 Receptor [01:20:09] – Werner Syndrome & Repair [01:20:30] – APOE & Alzheimer’s [01:20:52] – NF‑κB & Inflammation [01:21:01] – Telomerase & Aging [01:29:44] – Question 1: ABCD Model – Unisexual Flower [01:34:01] – Complete Session (Ageing Senescence | Developmental Biology) Topics Covered • Ageing vs Senescence Concepts • Cellular Senescence & Hayflick Limit • Telomere Theory & Replicative Ageing • Programmed & Damage Theories • CSIR PYQs & Problem-Solving Tricks Lecture Summary In this session, IFAS Expert Faculty focuses on Ageing Senescence, covering cellular senescence, Hayflick limit, telomere theory, and damage theories. Discusses oxidative stress, apoptosis vs senescence, and replicative ageing. Learn problem-solving tricks with CSIR NET & DBT JRF PYQs. Master Ageing Senescence concepts crucial for Developmental Biology. 🎯 Why IFAS is India's No. 1 Choice? (Our Results Speak): We have consistently produced Top Rankers in CSIR NET Life Sciaences. 🏆 CSIR NET Dec 2025: 4500+ Selections (AIR 3, 8, 9, 9, ...) 🏆 CSIR NET June 2025: 4100+ Selections (AIR 1, 2, 6, ...) 🏆 CSIR NET Dec 2024: 3000+ Selections (AIR 5, 6, 7, 8...) 🏆 CSIR NET June 2024: 2000+ Selections (AIR 3, 10, 13...) 🏆 CSIR NET Dec 2023: 1200+ Selections (AIR 2, 4, 5...) 📄 View Detailed Result Sheet: 📌 https://drive.google.com/file/d/1THh6... 🎯 Target Audience: This video is highly beneficial for students preparing for: 🚀 CSIR NET Life Science (June 2026) 🚀 GATE Biotechnology (BT) & Life Sciences (XL) 🚀 DBT JRF 🚀 MH SET, WB SET, K SET, & other State Eligibility Tests 🚀 M.Sc. & Ph.D. Entrance Exams 🔗 Important Links: 🌍 Visit our Website: https://ifasonline.com/csir-net/life-... 📞 Contact for Queries: 9172266888 📲 WhatsApp: https://api.whatsapp.com/send?phone=9... 🔥 Qualification Prediction (Free Tool): https://ifasonline.com/QualificationP... 📘 Get Detailed Free Counseling: https://ifasonline.com/csir-net/life-... 📲 Download IFAS App: 📌 Android: https://play.google.com/store/apps/de... 📌 Ios: https://apps.apple.com/us/app/ifas/id... 📘 Buy CSIR NET Life Science Books: 📌 https://ifasonline.com/csir-net/life-... 🔥 Our Social Media Platforms: 📌 Telegram: https://t.me/NET_GATE_SET_LifeScience... 📌 Instagram:   / csir_net_life_science_ifas   📌 Facebook:   / ifasls   📌 WhatsApp: https://api.whatsapp.com/send?phone=9... 💡 Stay Updated, Stay Ahead! This video has following search items #csirnet2026 #IFAS #GATE2026 #LifeScience #BiologyLecture #csirnet #csirnetlifescience #csirjrf #csirnetpreparation #csirugcnet #csirnetlifesciences #setlifescience #gatelifescience #gatebt #gatexl #complete #bestcoaching