Can a Vaccine Treat Pancreatic Cancer? | Stanford Cancer Institute Breakthroughs in Cancer seminar

Can RNA vaccines unlock new treatments for pancreatic cancer? In this Breakthroughs in Cancer seminar, Vinod Balachandran, MD, discusses the latest research on making "cold" tumors "vaccinable." Speaker: Vinod Balachandran, MD, Director, The Olayan Center for Cancer Vaccines, Associate Attending Surgeon, Memorial Sloan Kettering Cancer Center Chapters: 00:00 - Introduction 01:51 - Lecture: RNA Vaccines for Pancreatic Cancer 02:06 - Why immunotherapy often fails in pancreatic cancer 04:01 - Learning from the "10%": Natural immunity in survivors 06:16 - Predicting vaccine success: The Neoantigen Model 14:35 - Designing clinical trials for personalized RNA vaccines 16:03 - Results: Robust T-cell responses in patients 20:32 - How long does the vaccine protection last? 23:07 - Clinical outcomes and delayed recurrence 24:35 - Visualizing T-cells eliminating tumor cells 28:45 - Summary of vaccine mechanisms 43:16 - Future outlook: Scaling access to cancer vaccines 49:46 - Audience Q&A Learn more & Follow: Breakthroughs in Cancer Series: https://med.stanford.edu/cancer/about... Stanford Cancer Institute: https://med.stanford.edu/cancer.html LinkedIn:   / stanford-cancer   Instagram:   / stanford.cancer   X(Twitter): https://x.com/StanfordCancer X(Twitter): https://x.com/SCIDirector #CancerResearch #PancreaticCancer #mRNA #Oncology #StanfordCancer ‪@mskcc‬