Podophyllotoxin (Part 01)= Industrial Production (Isolation), Estimation and Utilization (Part 15)

Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/de... Podophyllotoxin Podophyllotoxinis is obtained from the root and rhizome of Podophyllum hexandrum Royle or Podophyllum emodi (Indian Podophyllum) and Podophyllum peltatum (American podophyllum). Family- Berberidaceae. Podophyllotoxin Isolation Commercial podophyllin is obtained by extraction of powdered rhizome/roots of P. emodii with methanol. Then it is reduced under vacuum. Semi-solid mass is put into acidulated water (10 ml HCl in 100 ml water). The precipitates are allowed to settle. Filtrate is decanted and then washed with cold water. Resin obtained is dried, and upon drying, it gives dark brown amorphous powder called podophyllin. The obtained powder is extracted with chloroform and further purification is done by repeated re-crystallization from benzene alone or alcohol benzene mixture followed by washing with petroleum ether/hexane yield podophyllotoxin. Get in touch with the solution by just clicking the following links- Facebook Group-   / solutionpharamcy   Mobile App - https://play.google.com/store/apps/de... New Channel (Pharmacy Dictionary)    / @pharmacydictionary   E-Mail for official and other work - [email protected] #solutionpharmacy #Pharmacologyclass #Pharmacognosyvideos #GPAT