7 SN1 vs SN2 Reactions

SN1 vs SN2 Reactions: Chad breaks down everything the undergraduate organic chemistry student needs to know regarding SN1 and SN2 reactions including substrate effects, nucleophile effects, solvent effects, and what makes a good leaving group. You'll also learn "back-side attack" in the SN2 mechanism that leads to inversion of configuration when it occurs at a chiral center, and about the carbocation intermediate in the SN1 mechanism that leads to racemization when the SN1 reaction occurs at a chiral center. Finally, Chad concludes the lesson working several SN1 vs SN2 examples so that you clearly understand how to distinguish between SN1 and SN2 reactions in terms of the substrate, nucleophile, and solvent and presents an SN1 vs SN2 chart to help students remember how to determine which mechanism is more likely for nucleophilic substitution. Happy Studying! 00:00 - Introduction to Nucleophilic Substitution Reactions 01:44 - SN2 Reactions 12:06 - Factors Affecting SN2 Reactions--Substrate Effects 17:33 - Factors Affecting SN2 Reactions--Nucleophile and Solvent Effects 25:03 - Factors Affecting SN2 Reactions--Leaving Group Effects 28:43 - SN1 Reactions 37:19 - Factors Affecting SN1 Reactions 45:20 - Carbocation Rearrangements in SN1 Reactions 52:43 - Unreactivity of Vinyl and Aryl (sp2) Halides 54:11 - Distinguishing Between SN1 and SN2 https://www.chadsprep.com/