Principal Component Analysis & ΔG Calculations Using GROMACS – Full Tutorial | Protein Dynamics

In this video, we delve into the fascinating world of molecular dynamics simulations by exploring Free Energy Landscapes (FELs) and Gibbs Energy plots. We'll walk you through how to interpret these plots, understand the significance of principal components (PC1 and PC2), and estimate Gibbs free energy from color-coded landscapes. Link to the script: https://github.com/pritampanda15/Mole... What You'll Learn: 1. How to interpret Free Energy Landscape (FEL) plots. 2. The role of principal components (PC1 and PC2) in Gibbs Energy calculations. 3. Estimating Gibbs Free Energy from color-coded regions. 4. Applications of these plots in biomolecular studies. If you found this video helpful, don't forget to like, subscribe, and share! Let us know in the comments if you have any questions or topics you'd like us to cover in future videos. ================================================================== Welcome to Omixium! This channel is dedicated to empowering the next generation of scientists with hands-on tutorials, deep dives, and tool walkthroughs in: 🔬 Bioinformatics & Computational Biology 🧠 AI in Drug Discovery & Protein Design ⚗️ Molecular Docking, MD Simulations & Systems Biology 🧬 Single-cell RNA-seq, Multi-omics & NGS Pipelines 👨‍💻 AI Coding for Biology (Claude, Gemini, GPT) 🧪 New videos every week — for scientists, students, coders, and curious minds! --- 🌐 Stay Connected: 🔗 LinkedIn: [Pritam Kumar Panda](  / pritam-kumar-panda  ) 🌍 Website: [https://www.atomodyssey.com](https://www.atomodyssey.com) 📧 Contact: [[email protected]](mailto:[email protected]) 💻 GitHub: [https://github.com/pritampanda15](https://github.com/pritampanda15)