Cyanide Poisoning USMLE Toxicology

Cyanide is a rapidly-acting, potentially lethal poison. Exposure can happen by administration of nitroprusside, or by inhalation in the setting of a fire. Cyanide exerts its effects by inhibiting Complex IV of the electron transport chain, thereby preventing aerobic respiration. The clinical picture is caused by reduced ability to utilize oxygen, and includes tissue hypoxia unresponsive to supplemental oxygen, cherry red skin discoloration, bright red venous blood, and almond breath odor. Treatment involves first administering nitrites and following with thiosulfate, although hydroxycobalamin can also be used. Subscribe for More: https://bit.ly/2yybxhm Study Interactive Image: https://pixorize.com/view/4764