Investigating the ubiquitin proteasome system

In today’s podcast Professor Selina Wray from University College London, meets four early career researchers, who know a great deal about the brain, human iPSC derived cells and the ubiquitin-proteasome pathway (not that isn’t a new type of electric car). We’ll be discussing their research, discovering more about super resolution microscopy, and how they’re researching the ubiquitin proteasome system, and its connection to dementia. We’re delighted to welcome our guests: PhD Students Liina Sirvio, Katiuska Daniela Pulgar Prieto from the UK Dementia Research Institute at Imperial College London. Georgie Lines, PhD Student from University College London and Dr Emma Mee Haynes a Postdoctoral Research Associate also from the UK Dementia Research Institute at Imperial College London. What is the purpose of ubiquitin proteasome system? In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. You can find out more about our guests, and access a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.a... _________________________ Finally, please review, like, and share our podcast - and don't forget to subscribe to ensure you never miss an episode. Register on our website to receive your weekly bulletin, and to access more great content – blogs, science, career support + much more www.dementiaresearcher.nihr.ac.uk This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support. ~-~~-~~~-~~-~ Learn more about the new drugs coming to treat Alzheimer's Disea with this video podcast - "A Closer Look at Lecanemab, Donanemab and Amyloid"    • A Closer Look at Lecanemab, Donanemab and ...   ~-~~-~~~-~~-~