2026 SC INBRE Biostatistics Summer Courses Week 3, Day 4 (June 18)

WEEK 3 (June 15-19): Bioinformatics & High-Dimensional Data Target: Genomics workflows, dimensionality reduction, penalized regression, and reproducible reporting. Thursday, June 18, Day 14 MORNING – Dimensionality Reduction and Penalized Regression PCA and its geometric interpretation; scree plots; biplots; introduction to LASSO/ridge/elastic net; coordinate descent; tuning λ. AFTERNOON – PCA and glmnet Lab prcomp() and factoextra for PCA; fitting penalized regression with glmnet; cross-validated λ selection; coefficient path plots; interpreting sparse solutions. Learn more at https://www.scinbre.org/learning/bids...