Sepsis y Shock Séptico: Reanimación, Lactato, Vasoactivos y Manejo Clínico REAL

Sepsis and septic shock remain a leading cause of mortality in internal medicine and critical care. In this second part of the Sepsis class, we address real-world clinical management, based on pathophysiology and a practical approach, just as you would encounter it in the ER, ICU, or ward. 📌 What will you learn in this class? What exactly is tissue perfusion and what does it depend on? Relationship between oxygen delivery (DO₂) and oxygen consumption (VO₂) Correct interpretation of lactate in sepsis (hyperlactatemia ≠ hypoperfusion) Clinical targets: MAP, urine output, capillary refill, ScvO₂ Rational use of vasoactive agents (norepinephrine, vasopressin, epinephrine) Role of inotropes in low cardiac output Empirical antimicrobial management in sepsis and septic shock Prevention of shock-related complications 📚 Class based on: NEJM – Sepsis and Septic Shock (2024) Surviving Sepsis Campaign 2021 Harrison, Guyton & Hall, and classic and modern evidence 🎯 This class is designed for students, interns, residents, and physicians who want to understand sepsis, not just memorize algorithms. 👉 Part 1 available on the channel 📺 Internal Medicine Education #Sepsis #SepticShock #InternalMedicine #ICU #EmergencyRoom #IntensiveCare #Resuscitation #Lactate #VasoactiveDrugs #Norepinephrine #TissuePerfusion #Pathophysiology #DO2VO2 #NEJM #SurvivingSepsis #MedicalEducation #Interns #Residents #Physicians #InternalMedicineEducation 00:00:00 Introduction 00:01:00 Tissue Perfusion 00:02:09 Oxygen Delivery and Consumption 00:04:15 MAP and Perfusion 00:06:13 DO2/VO2 Ratio 00:09:50 Fluids in Sepsis 00:11:13 Lactate in Sepsis 00:14:43 Capillary Refill in Sepsis 00:17:43 SVC and PVC 00:18:38 Vasoactive drugs, corticosteroids, and inotropes 00:21:48 Antibiotics in sepsis