Rosanna Arquette Gets Brutally Honest About Aging, Sex & Hormones

Rosanna Arquette joins Melissa Rivers for a brutally honest conversation about Hollywood, aging, family trauma, and finally choosing herself. On this episode of Melissa Rivers’ Group Text, Rosanna opens up about being dismissed by the industry, why she left Hollywood to heal after her divorce, navigating aging and hormones, and the painful reality of how women are treated when money is the only priority. From iconic films like Desperately Seeking Susan and Pulp Fiction to modern industry hypocrisy, Rosanna holds nothing back in this raw, funny, and deeply human conversation. 00:00 Rosanna Arquette Joins the Group Text 01:00 Getting Cast by Charli XCX 01:30 “What Even Is Brat Summer?” 02:20 Satirizing the Music Industry 03:30 Playing a Ruthless Record Executive 04:25 “It’s Only About the Money” 05:34 Hollywood Takes Itself Too Seriously 06:26 Improvisation vs Scripted Acting 07:16 Inside Baseball or For Everyone? 08:18 Throwing People Under the Bus 09:08 Anxiety Before Every Project 10:27 Working With Tarantino & Scorsese 11:56 Brain Fog, Aging & Hormones 12:25 Why Rosanna Won’t Do Hormone Therapy 13:49 Growing Up in the Arquette Family 15:02 Losing Alexis & Family Trauma 16:47 The Arquette Family Group Text 17:56 Dating, Divorce & Starting Over 19:14 Why She’ll Never Use Dating Apps 21:48 Being an “Unhinged” Mom 22:04 Protecting Her Daughter From Hollywood 23:15 Culture, Accountability & Resistance 23:38 Leaving Hollywood to Heal 26:05 Two Houses, Not One 26:52 Not Being Invited to Her Own Premiere 28:17 Full-Circle Hollywood Irony 29:12 Final Thoughts & What’s Next