QUALITY-BY-DESIGN IN SPRAY DRYING PROCESSES – TRANSFER LAB TO PRODUCTION

Present by Sune Klint Andersen at Janssen Pharmaceutical Companies of Johnson & Johnson and João Vicente Senior Scientist - Particle Engineering Team Leader at Hovione. Spray drying is a continuous and scalable manufacturing process commonly used in the pharmaceutical industry. Due to its scalable and continuous nature, it is possible to apply Quality-by-Design (QbD) and Process Analytical Technologies (PAT) early on in the development of a spray drying process. Knowledge gained from QbD e.g. Design-of-Experiments (DoE) and PAT increase process understanding and the knowledge can be readily applied when scaling up the process and in production scale application of PAT i.e. especially with respect to the control strategy. The Webinar will discuss the application of QbD early in the development and how the obtained knowledge can be used to optimize the transfer of the spray drying process to production scale including PAT strategy.