Mitophagy in Neurodegenerative Diseases and Molecular Mechanisms of Protection
In this webinar, Elena Ziviani, PhD, a professor of biochemistry at the University of Padova, whose research deciphers the mechanisms of mitochondrial quality control, discusses how promoting mitophagy through calcineurin activation or USP14 inhibition provides a PINK1/Parkin-independent pathway to clear dysfunctional organelles, offering a promising therapeutic strategy for Parkinson’s disease. Mito911 is a webinar series hosted by Team Hurley, which is part of the Aligning Science Across Parkinson's (ASAP) Collaborative Research Network (CRN). This series discusses the latest research in mitochondrial biology, autophagy, and neurodegeneration. Stay connected! 🔗 Website: https://parkinsonsroadmap.org/# LinkedIn: / asap-research Bluesky: https://bsky.app/profile/asapresearch... This video continues the conversation from a previous video on the metabolic vulnerability of synaptic vesicle recycling and how the local regulation of ATP and GTP serves as a critical neuroprotective mechanism against Parkinson’s disease. Watch the video: • Metabolic Vulnerabilities in Neurodegenera...

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