Developing An In Vivo CAR-T With Interius BioTherapeutics' Sianny Christanti and Babu Medi, Ph.D.

On this episode of Better Biopharma, Interius BioTherapeutics’ Sianny Christanti and Babu Medi, Ph.D., explain how the company is re-engineering a lentiviral vector to enable INT2104, its off-the-shelf, in vivo CAR T-cell therapy. They discuss the vector's design and its manufacturability, as well as the analytical and regulatory challenges of bringing this first-in-human therapy to the clinic. Follow Tyler Menichiello on LinkedIn:   / tmenichiello   Keep up with everything biomanufacturing at Bioprocess Online: https://www.bioprocessonline.com/ Subscribe to our newsletters: https://www.bioprocessonline.com/user... -- Subscribe to the podcast! Apple - https://podcasts.apple.com/us/podcast... Spotify - https://open.spotify.com/show/3dvQdIL... YouTube -    • Better Biopharma  

January 30, 2025 - Admissions Webinar - MSE-AI Online with Program Director Chris Callison-Burch
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January 30, 2025 - Admissions Webinar - MSE-AI Online with Program Director Chris Callison-Burch

Recent Highlights in Targeted Protein Degradation
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Recent Highlights in Targeted Protein Degradation

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In Vivo CAR T-Cell Therapeutics With Umoja Biopharma's Dr. Andrew Scharenberg

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Ummi Lawan - Harmony Legal Group

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Trump Sends Vance to Concede to Iran & Reflecting Pool Is Filled with Corruption | The Daily Show

How ASML Makes Chips Faster With Its New $400 Million High NA Machine
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How ASML Makes Chips Faster With Its New $400 Million High NA Machine

How AI Cracked the Protein Folding Code and Won a Nobel Prize
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How AI Cracked the Protein Folding Code and Won a Nobel Prize

Digital Asset Treasuries Under Pressure, IMF Warns of Tokenization Risks | Bloomberg Crypto 4/7/2026
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Digital Asset Treasuries Under Pressure, IMF Warns of Tokenization Risks | Bloomberg Crypto 4/7/2026

Cell Therapy Without The Cells: Building A Therapeutic Secretome With Noveome’s Larry Brown, Sc.D.
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Cell Therapy Without The Cells: Building A Therapeutic Secretome With Noveome’s Larry Brown, Sc.D.

Europe Has Become a War Project — Can It Be Stopped? | Yanis Varoufakis & Jeffrey Sachs
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Europe Has Become a War Project — Can It Be Stopped? | Yanis Varoufakis & Jeffrey Sachs

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Could Cell Therapy Change Autoimmune Disease? A Closer Look at CAR T Therapy

Maggie Haberman & Jonathan Swan - On “Regime Change” & Inside The Trump Presidency | The Daily Show
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Maggie Haberman & Jonathan Swan - On “Regime Change” & Inside The Trump Presidency | The Daily Show

AlphaFold - The Most Useful Thing AI Has Ever Done
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AlphaFold - The Most Useful Thing AI Has Ever Done

Elisabeth De Dobbeleer & Jason Gallo - Cisco 360 Partner Program Deep Dive | Partnerships Unraveled
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Elisabeth De Dobbeleer & Jason Gallo - Cisco 360 Partner Program Deep Dive | Partnerships Unraveled

AI Is Creating A Rare Opportunity For Investors. How Jim Roppel Is Playing It. | Investing With IBD
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AI Is Creating A Rare Opportunity For Investors. How Jim Roppel Is Playing It. | Investing With IBD

The skill of self confidence | Dr. Ivan Joseph | TEDxRyersonU
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The skill of self confidence | Dr. Ivan Joseph | TEDxRyersonU

Webinar: In Vivo Preclinical Efficacy & Safety of CAR-T, -NK, and -Myeloid Based Therapies
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Webinar: In Vivo Preclinical Efficacy & Safety of CAR-T, -NK, and -Myeloid Based Therapies

How do successful health programs move from research findings to real-world impact?
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How do successful health programs move from research findings to real-world impact?

FPN Webinar: CIDP, From Soup to Nuts, with Sami Khella, MD
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FPN Webinar: CIDP, From Soup to Nuts, with Sami Khella, MD

The Investment Conversation: Public and Private Credit Markets Converge
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The Investment Conversation: Public and Private Credit Markets Converge