Michael Reactions | 21.8 Organic Chemistry

Chad provides a comprehensive lesson on Michael Reactions which involve conjugate or 1,4-addition to a conjugated ketone. A conjugated ketone is referred to as the Michael acceptor and typical Michael donors include the enolate of a beta-diketone and organocuprates (Gilmann reagents). A detailed mechanism with arrow-pushing is included and examples showing how the choice of nucleophile is the distinction of whether 1,2-addition or 1,4-addition occurs. Do you want Chad’s Organic Chemistry Study Guides and Practice Quizzes/Tests? Check out Chad’s Organic Chemistry Master Course: https://www.chadsprep.com/organic-che... 00:00 Lesson Introduction 00:50 Michael Reactions: Michael Donors and Acceptors 06:38 Michael Reaction Example 08:48 1,2-Addition vs 1,4-Addition https://www.chadsprep.com/ #organicchemistry #organicchemistrytutorial