Biologics for Chronic Rhinosinusitis with Nasal Polyps w/ Dr. Reena Mehta | ENT Ep. 235

How do we integrate biologics into the existing stepwise treatment model for chronic rhinosinusitis with nasal polyps (CRSwNP)? In this episode, Dr. Reena Mehta, an allergist from Uptown Allergy and Asthma in New Orleans, discusses the use of biologics for treating chronic rhinosinusitis with nasal polyps. --- SYNPOSIS Dr. Mehta elaborates on the common presentations of patients, the role of biologics such as dupilumab and tezepelumab, and the nuances of patient management post-sinus surgery. Dr. Mehta also covers the workup process, the significance of patient comorbidities like asthma and allergies, and the future perspectives on biologic treatments. Practical aspects of biologic therapy, including insurance hurdles, patient compliance, and the effectiveness of various biologics are thoroughly examined. --- TIMESTAMPS 00:00 - Introduction 02:27 - Understanding Chronic Rhinosinusitis with Nasal Polyps & Presentation 05:22 - Workup and Management of Nasal Polyps 07:31 - Treatment Options: Steroids and Biologics 15:28 - Tezepelumab: A New Tool in the Toolkit 25:03 - Side Effects and Safety of Biologics 28:59 - Insurance and Approval Challenges 36:14 - Long-Term Safety and Efficacy 38:47 - Pediatric Considerations and Future Directions 41:37 - Collaboration Between ENT and Allergy Specialists 45:07 - Conclusion and Final Thoughts --- RESOURCES Dr. Reena Mehta https://uptownallergyasthma.com/aller... --- The BackTable ENT Podcast is a resource for otolaryngologists to learn tips, techniques, and practical advice on all things ear, nose, and throat. Tune in to the BackTable ENT Podcast every week for candid conversations about rhinology, laryngology, otology, and head and neck surgery. Get notified when new episodes drop! Subscribe to the BackTable ENT Podcast on your go-to podcast platform, and follow us on your social media platform of choice for regular otolaryngology updates. ► https://www.backtable.com/shows/ent/s... #ENT235 #immunology #allergy #biologics