The Past, Present, and Future of Lewy Body Dementia

Recorded at the King’s Conference Centre in Southampton this talk was delivered as part of the Wessex Dementia Research Conference 2025 on 2nd July 2025. In this talk, Professor John O'Brien from University of Cambridge explores the history, current understanding, and future of Lewy body dementia (LBD). He reflects on the early pathological discoveries, including the naming debates, and how LBD came to be recognised as a distinct condition. The session covers clinical features, diagnostic criteria, and how biomarkers such as DAT scans and REM sleep analysis are used today. Professor O'Brien discusses the challenges of accurate diagnosis, under-recognition in clinical settings, and the importance of regular reassessment. He also shares updates on promising areas of research, diagnostic tools, and clinical trials aimed at improving outcomes and developing future treatments. -- Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch: https://www.dementiaresearcher.nihr.a... -- Follow us on Social Media:   / dementia_researcher     / dementia.researcher     / demrescommunity     / dementia-researcher   https://bsky.app/profile/dementiarese...