Ketamine vs Esketamine (Spravato): What’s the Difference?

Ketamine vs Esketamine (Spravato): What’s The Difference, and Which Works Better? Ketamine, also called racemic ketamine, contains two mirror-image forms of the same molecule: S-ketamine (esketamine) and R-ketamine (arketamine). Esketamine (Spravato) is one of these two forms of the molecule. Esketamine is often delivered intranasally and racemic ketamine is often delivered intravenously (IV). The “mirror-image” difference and the way they're typically administered make a difference. The racemic mixture of ketamine looks to be more effective than either esketamine or arketamine alone, and IV ketamine infusions are more available, and can be more carefully controlled, than other methods of delivery including intranasal administration. While both may be effective, compared to intranasal esketamine, or Spravato, the information we have suggests that IV infusions of ketamine are more effective. Full Written Summary: https://wellsmedicine.com/ketamine-vs... About Wells Medicine: Wells Medicine is a Houston-based practice designed to provide meaningful care for mental health. Providing targeted interventional treatments for Depression, Anxiety, OCD, PTSD and other conditions, with Ketamine Treatments, Stellate Ganglion Blocks, TMS, and Nitrous-Oxide Treatments. Focused on comprehensive care and integration with Psychiatry, Psychology, and Support Services. We are evidence-based, patient-focused and mission-driven. Important Disclaimer: The content here is for informational purposes and should not be relied upon for medical decisions. For the details of your specific medical conditions and treatments consult your doctors or other qualified healthcare professionals.