Pleiotropy | One Gene Multiple Phenotypic Effects | NEET Biology Class 12 | Neela Bakore Tutorials

◀ PREVIOUS VIDEO (9/36): Multiple Allelism (ABO Blood Groups)    • Multiple Allelism & ABO Blood Groups | IA ...   ▶ CURRENT VIDEO (10/36): Pleiotropy    • Pleiotropy | One Gene Multiple Phenotypic ...   ▶ NEXT VIDEO (11/36): Complementary Genes (9:7)    • Complementary Genes 9:7 Ratio | Gene Inter...   ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 🔗 Full Playlist:    • Playlist   One gene — many effects! Pleiotropy explained with NEET-relevant examples. 📌 Topics Covered: • Definition and concept of Pleiotropy • Pleiotropy vs Polygenic inheritance • Example 1: Sickle Cell Anaemia gene • Example 2: Drosophila vestigial wing gene • NEET MCQ practice tips Transcript with Timestamp 0:00 Introduction — Pleiotropy 0:16 One gene controls MORE than one character 0:56 Example — Sickle Cell Anaemia 1:12 Normal haemoglobin — 2 alpha + 2 beta polypeptide chains 1:34 Point mutation in beta chain — autosomal recessive 2:09 Normal vs Sickle Cell beta chain — amino acid position 6 3:14 Position 6: Glutamic acid (normal) → Valine (sickle cell) 5:42 Effect 1: Change in haemoglobin structure — reduced oxygen carrying capacity 6:00 Effect 2: Change in RBC shape — biconcave → sickle shaped 6:49 ONE gene → TWO effects = Pleiotropy 8:22 Genotype notation: HBᴬ HBᴬ (normal), HBᴬ HBˢ (carrier), HBˢ HBˢ (diseased) 10:30 Sickle cell trait confers RESISTANCE to malaria Complete Study Notes (11th and 12th) are available at: https://amzn.to/3K4Li7k Complete Study Notes for 12th are available at: https://amzn.to/3PRhWjm Complete Study Notes for 11th are available at: https://amzn.to/4uw1hBa The study notes for this unit Genetics & Evolution are available at https://amzn.to/2Sh27jW The study notes for other units: - Diversity in Living World - https://amzn.to/3r8qkyH Structural Organisation in Plants and Animals - https://amzn.to/3r2cxmZ Cell: Structure and Functions - https://amzn.to/2GPagcm Plant Physiology - http://amzn.to/2EZR5HS Human Physiology - http://amzn.to/2DA46ea Reproduction - https://amzn.to/2wu43eS Biotechnology - http://amzn.to/2EZyqf9 Biology in Human Welfare https://amzn.to/4dPRZd7 Ecology https://amzn.to/3RwuOvF ____________________________________________ For business inquiries: [email protected] ___________________________________________ #Pleiotropy #PleiotropicGene #GeneticsClass12 #NEETBiology #NeelaBakoreTutorials #PrinciplesOfInheritance