Enactivism, Buddhist Epistemology & the Cosmic Play with Hüseyin Beyköylü

Hüseyin Beyköylü left medicine for cognitive science after an LSD experience, and five years later he's arguing that mainstream psychology and neuroscience are built on assumptions that systematically miss what matters most about the mind. This is a dense, careful conversation about epistemology, metaphysics, and why randomized controlled trials can't capture human transformation. We get into the entropy-fluency hypothesis, how destabilization and reorganization cycle through every scale from insight to mystical experience, and why false fluency (the smoothness of a conspiracy theory, the comfort of a simplified worldview) is just as real as the real thing. In the second half, the conversation opens into metaphysics: what is truth, is there a ground, and does groundlessness mean nothing matters? Hüseyin draws on Madhyamaka, Spinoza, Karen Barad, and Varela to argue that reality is a cosmic play we actively participate in, and that truth is something you embody rather than correspond to. TIMESTAMPS 0:00:00 - Start 0:00:35 - Introduction & Hüseyin's Background 0:02:16 - From Medicine to Psychedelic Research: The LSD Pivot 0:05:05 - Overview of Published Papers 0:06:31 - The 4P Model: Four Ways of Knowing 0:10:55 - Are the Categories Real? Yogacara, Madhyamaka & Reflexivity 0:17:53 - Language of Description vs. Language of Training 0:23:15 - What's Wrong with Therapy? Non-Propositional Transformation 0:28:18 - The Woo Problem: How to Evaluate Alternative Therapies 0:34:57 - Ergodicity, Idiographic Science & Complex Systems 0:43:31 - Hüseyin's Empirical Research: Time Series & Phase Transitions 0:48:42 - The Cognitive Continuum: From Fluency to Mystical Experience 0:55:48 - Relevance Realization & the Entropy-Fluency Hypothesis 1:02:24 - False Fluency, Conspirituality & Context-Dependence 1:12:23 - The Biggest Problems with Psychedelic Science & Neurophenomenology 1:27:39 - What Is Truth? Groundlessness, the Sacred & the Cosmic Play 2:05:57 - What Would You Tell Your Younger Self? KEY INSIGHTS & TRANSCRIPT https://tiagovf.com/posts/podcast-ena... FOLLOW MY WORK https://substack.com/@tiagovf   / tiagobooks   MUSIC CREDIT Intro song by Lief Sjostrom, titled Peril, from the album 'Impossible Parade' Website: https://liefsjostrom.com/ Album: https://liefsjostrom.bandcamp.com/alb...