Reclassifying HER2: What Oncologists Need to Know About HER2-Low and -Ultralow Breast Cancer

Dr. Sara Nunnery, director of breast cancer research at Tennessee Oncology, discusses the evolving classification of HER2-low and HER2-ultralow breast cancer, and the clinical implications of the DESTINY-Breast06 trial. She explains how precise pathology reporting is key to identifying eligible patients and offers insights into how Enhertu (trastuzumab deruxtecan) is changing treatment decisions in HR-positive, HER2-low metastatic breast cancer. #breastcancer #her2 #enhertu #oncology #cancerresearch #medtwitter

Breast Cancer: MUST know details (ER, PR, HER2, Ki67, etc)
▶︎

Breast Cancer: MUST know details (ER, PR, HER2, Ki67, etc)

Metastatic breast cancer: Understanding HER2-low and HER2-ultralow classification
▶︎

Metastatic breast cancer: Understanding HER2-low and HER2-ultralow classification

Understanding Enhertu for HER2-Low & HER2+ Metastatic Breast Cancer
▶︎

Understanding Enhertu for HER2-Low & HER2+ Metastatic Breast Cancer

Lump to Breast Cancer - Alison | Triple Positive Breast Cancer | The Patient Story
▶︎

Lump to Breast Cancer - Alison | Triple Positive Breast Cancer | The Patient Story

Breast Cancer Recurrence: Am I Cured?
▶︎

Breast Cancer Recurrence: Am I Cured?

My Urgent Breast Cancer Screening Experience! Age 31💖
▶︎

My Urgent Breast Cancer Screening Experience! Age 31💖

Defining HER2-Low and HER2-Ultralow Breast Cancer
▶︎

Defining HER2-Low and HER2-Ultralow Breast Cancer

HER2-Low Breast Cancer: Treatment Options and What You Should Know
▶︎

HER2-Low Breast Cancer: Treatment Options and What You Should Know

Metastatic Breast Cancer: What You Need to Know
▶︎

Metastatic Breast Cancer: What You Need to Know

2025 Best of Breast - Clinical Case Discussions: 1) Metastatic, ER+ Case; 2) HER2 Positive Case
▶︎

2025 Best of Breast - Clinical Case Discussions: 1) Metastatic, ER+ Case; 2) HER2 Positive Case

Breast Site Group Presentation: HER2-Low & HER2-UltraLow Metastatic Cancer - November 20, 2025
▶︎

Breast Site Group Presentation: HER2-Low & HER2-UltraLow Metastatic Cancer - November 20, 2025

Why NO Follow-Up Scans After Breast Cancer? The Truth About Imaging
▶︎

Why NO Follow-Up Scans After Breast Cancer? The Truth About Imaging

Clear Margins… But Risk Remains
▶︎

Clear Margins… But Risk Remains

Targeted Therapy for HER2-low and HER2-ultralow Advanced Breast Cancer.
▶︎

Targeted Therapy for HER2-low and HER2-ultralow Advanced Breast Cancer.

Why Some Women Say No to Mammograms: The Hidden Dangers in Traditional Breast Cancer Screening
▶︎

Why Some Women Say No to Mammograms: The Hidden Dangers in Traditional Breast Cancer Screening

What's the Best Diet for Hormone Receptor-Positive Breast Cancer? The Ultimate Guide for HR+
▶︎

What's the Best Diet for Hormone Receptor-Positive Breast Cancer? The Ultimate Guide for HR+

Metastatic HR+/HER2- Breast Cancer Case | CDK4/6 Inhibitors, CNS Progression & Treatment Strategies
▶︎

Metastatic HR+/HER2- Breast Cancer Case | CDK4/6 Inhibitors, CNS Progression & Treatment Strategies

Highlights - Metastatic breast cancer: Understanding HER2-low and HER2-ultralow classification
▶︎

Highlights - Metastatic breast cancer: Understanding HER2-low and HER2-ultralow classification

Breast Cancer: Ductal Carcinoma in Situ (DCIS) EXPLAINED
▶︎

Breast Cancer: Ductal Carcinoma in Situ (DCIS) EXPLAINED

Hormone Replacement After Breast Cancer? What Every Woman Deserves to Know
▶︎

Hormone Replacement After Breast Cancer? What Every Woman Deserves to Know