OS SINTOMAS QUE PODEM INDICAR UM CÂNCER DE PÂNCREAS (DR. ÁRLEM PÉREZ) | Na Saúde x Na Doença #052

Did you know that pancreatic cancer is one of the most silent and dangerous cancers? Most patients discover the disease late because the symptoms are subtle and can be confused with common digestive problems. In episode 52 of the "In Health vs. Disease" Podcast, host Dr. Rafael Monteiro welcomes Dr. Árlem Pérez, a physician and digestive system surgeon, for a comprehensive discussion about the signs that shouldn't be ignored, which tests help with early diagnosis, and why paying attention to detail can save lives. Check out the main topics covered, with timelines: 01:21 - Where is the Pancreas and Why is Surgery Complex? 02:14 - Pancreas Functions: Endocrine (Diabetes) and Exocrine (Fat Digestion) 03:07 - Pancreas: Dual Function (Endocrine in the Blood and Exocrine in the Intestine) 03:59 - Pancreas Anatomy: Head/Neck and Body/Tail 04:56 - The Tumor: Most Common in the Pancreatic Head (Confluence of Ducts) 05:33 - Pancreas and Liver: The Bile Duct (Bile Duct) Passes Through It 06:46 - Pancreatic HEAD Cancer Symptom Triad 07:18 - Symptom #1: Jaundice (Yellowish Skin and Coca-Cola-Colored Urine) 07:43 - Symptom #2: Severe Abdominal Pain and Back Pain 08:10 - Back Pain: Sign of Advanced Tumor (Nerve Infiltration) 09:05 - Characteristics of Tumor Pain (Continuous, Unrelieved by Position/Analgesics) 09:48 - Antalgic Position and the Difference from Pancreatitis (Mohammedan Position) 10:30 - Jaundice and Intense Itching (Pruritus): Bile Impregnation 12:21 - Symptom #3: Marked Weight Loss (Cachexia) 12:55 - Why Does Weight Loss Happen? (Intense Metabolism, Lack of Appetite, Malabsorption) 15:18 - Aggressive Cancers: Pancreas, Stomach, and Esophagus (High Metabolism and Lack of Appetite) 15:53 ​​- Prognosis: Why Is Survival Short? (Difficulty of Early Diagnosis) 16:15 - Statistics: 70 to 80% of Cases Are Diagnosed at an Advanced Stage 16:47 - Cure and Recurrence: 5-Year Survival Rate (5%) and High Recurrence at 2 Years 17:42 - Risk Factor #1: Diet (Fats, Fiber, and Healthy Habits) 18:38 - Risk Factor #2: Chronic Pancreatitis (Alcohol-Induced) 19:00 - Risk Factor #3: Smoking (Main Direct Risk) 20:30 - Fun Fact: Alcohol Prefers to Attack the Pancreas OR the Liver, Rarely Both 24:50 - Risk Factor #4: Family History (1st Degree) and Hereditary Pancreatitis 25:51 - Chronic Pancreatitis: Slow Progression, Pain Insidious and Increased Cancer Risk 27:38 - Diabetes: Cause OR Consequence of Pancreatic Cancer? 28:20 - Cancer/Diabetes Relationship: Sudden Discovery of Diabetes (2-3 Months Before) 29:17 - Pancreatic Cancer Screening: Not Recommended (Except in Specific Cases) 29:55 - Pancreatic Cancer Speed: Rapid Growth (6 Months to 1 Year) 31:06 - Screening Limitations: CT (Radiation) and Endoscopic Ultrasound (Cost/Invasive) 32:46 - Tumor Marker CA 19-9: Not Used for Screening (False Positive) 34:58 - Why Not Use CA 19-9 in the Entire Population? (Does Not Reduce Mortality) 38:38 - Cancer and Normal CA 19-9: The False Negative (5 to 10% of Cases) 38:55 - Use of CA 19-9: Post-Treatment Follow-up (Check for Recurrence) 39:52 - Diagnosis: Is a Biopsy Always Mandatory? (CT Scan, CA 19-9, and Clinical Scenario) 41:13 - When Biopsy is NOT Mandatory (Resectable Tumor and NCCN Consensus) 41:38 - MANDATORY Biopsy: Advanced Cases or Pre-Chemotherapy 41:51 - Biopsy Risk: Serious Complications Are Rare (Higher Risk of False Negatives) 43:52 - Treatment: Surgery is ESSENTIAL for a Cure 44:26 - Surgery: Partial Removal of the Pancreas (Preservation of Body and Tail) 45:12 - NEOADJUVANT Chemotherapy (Before Surgery): It Is the Current Standard 46:13 - Major Advantage of Chemotherapy: Increased Survival (Systemic Disease) 47:20 - Chemotherapy in Practice: Controlling Localized Cancer and Improving Prognosis 48:05 - Unresectable Cases: Chemotherapy and Radiation Therapy (Improving Survival) 48:38 - Future of Treatment: Personalized Medicine and Immunotherapy (CAR T-Cell) 49:37 - Side Effects of Chemotherapy (Folfirinox): Nausea, Vomiting, Diarrhea, and Tingling 51:00 - Post-Diagnosis Survival: Today It's Greater than 6 Months (11 to 22 Months or More) 52:45 - Message of Hope: The Future of Immunotherapy and Cancer as a Chronic Disease 55:10 - Message of Support: Family is the Foundation (Dealing with the Cancer "War") 👉 Watch until the end—the last sign is the most overlooked! 👉 Share this video: it could literally save someone you love. EPISODE: SYMPTOMS THAT MAY INDICATE PANCREATIC CANCER (DR. ÁRLEM PÉREZ) | In Health vs. Sickness #052 ----------------------------------------------------------------------- Host: Dr. Rafael Monteiro @drrafaelmonteiro Guest: Dr. Árlem Pérez @arlemperez Your mark on the In Health vs. Sickness PODCAST: [email protected] #pancreascancer #nasaudexnadoencapodcast #podcast