Çıktı Evet Peki Şimdi Ne çıkacak? I Nörodejeneratif Hastalıklar

Neurodegenerative Diseases | The Exam Is Over, What's Next? | TUS Pathology In this video, I covered neurodegenerative diseases with a focus on the TUS exam. In the previous part of the series, I examined glomerulonephritis and kidney diseases; this time, I focused on neurodegenerative pathologies, which have a high weight in the exam. I explained the entire subject, from Alzheimer's to Parkinson's, ALS to prion diseases, in a way suitable for exam practice and using keywords. In the video, I particularly emphasized the following topics: Characteristic bodies and disease matching: Lewy body → Parkinson's / LBD | Neurofibrillary tangle + Neuritic plaque → Alzheimer's | Bunina body → ALS | Spongioform degeneration → Prion (CJD) Protein accumulation table: α-Synuclein → Parkinson's | Tau → Alzheimer's + FTD + Parkinson Plus | β-Amyloid (Aβ42) → Alzheimer's | Huntington's (CAG repeat) → Huntington's | SOD1 / TDP-43 → ALS Alzheimer details: APP (chromosome 21) → β-amyloid | Early Alzheimer's in Down syndrome | Hirano body + granulovacuolar degeneration | APOE ε4 risk allele | Correlation with dementia → neurofibrillary tangle count (not plaque!) Motor neuron diseases: ALS → Upper + Lower MN; eye movements and sensation are PRESERVED | SMA → Only Lower MN, autosomal recessive, SMN1 | Kennedy → X-linked, CAG repeat, gynecomastia + testicular atrophy Confused points: Parkinson vs LBD (both have Lewy bodies, different order of onset!) | CJD vs vCJD (difference in age and psychiatric onset) | "Boxing glove" CT appearance in Huntington's → caudate nucleus + putamen atrophy Atypical Parkinsonism: PSP → tauopathy, difficulty with voluntary eye movement | MSA → synucleopathy, Parkinsonism + cerebellar ataxia + autonomic triad | Both show minimal response to L-DOPA! At the end of the video, in the "So What's Next?" section, I solved case-based questions in formats you might directly encounter in the exam. I prepared this content especially for medical students and resident candidates preparing for the TUS exam. The topic is summarized using keywords and pathology clues that facilitate quick recall. You can reach me in the comments section with any points you don't understand or topic suggestions. I actively monitor comments. 🌐 drpatoloji.com 📸 Instagram: @drpatoloji ✈️ Telegram: https://t.me/drpatoloji #TUSPathology #NeurodegenerativeDiseases #TUSPreparation #Alzheimer #Parkinson #ALS #Huntington #PrionDiseases #TUS2026 #NeuropathologyTUS #LewyBody #TauProtein #DrPathology #MedicalSpecialization #TUSVideos