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In this video, you will learn how to find hub genes by STRING Database and how to construct network by using Cytoscape. The Cytoscape software can be freely downloaded from https://cytoscape.org/download.html Using CytoHubba, a powerful plugin in Cytoscape, we'll guide you through the process of identifying hub genes in biological networks step-by-step. From loading your network data to running advanced algorithms, you'll learn everything you need to know to uncover the hidden hubs in your biological system. What are hub genes? In gene networks • Genes that have many interactions with other genes are defined as hub gens. • More important genes mean more interaction to other genes (more degree) • Less important genes mean less interaction to other genes (less degree) • We fine top most (10-15) important genes

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