The INCREDIBLE Biology of a Nearly Unkillable Bacteria

🤝 Support the channel by checking out our revamped Patreon:   / clockworkshow   🦠 Deinococcus Radiodurans can survive over 1000x the dose of ionizing radiation that can kill a person. Scientists have thrown simulated asteroid impacts at this little critter and left it on the exterior hull of the international space station, only for D. radiodurans to SURVIVE. Let's explore the astounding biochemistry of D. radiodurans and discover how such a tough biological system could have emerged here on Earth. 💥I made this episode after hearing about d. radiodurans from the brilliant folks at ‪@FromFirstPrinciplesPod‬ -- check them out, and specifically their exploration of a recent d. radiodurans paper here:    • Astrobiology’s Biggest Survival Test + A V...   ⚡True Manganese Enjoyers watch Tatefacts with ‪@MQTate‬ :    • Tatefacts: Manganese   ⬣ Everyone knows that hexagons are the bestagons:    • Why Hexagons Waste the Least Space   💻 Rendered using @BradyJohnston 's open-source Molecular Nodes Add-on for Blender: https://extensions.blender.org/add-on... 📚Primary Works Cited: Cox, M., Battista, J. Deinococcus radiodurans — the consummate survivor. Nat Rev Microbiol 3, 882–892 (2005). https://doi.org/10.1038/nrmicro1264 Krisko A, Radman M. Biology of extreme radiation resistance: the way of Deinococcus radiodurans. Cold Spring Harb Perspect Biol. 2013;5(7):a012765. Published 2013 Jul 1. doi:10.1101/cshperspect.a012765 A. von Kügelgen,S. van Dorst,K. Yamashita,D.L. Sexton,E.I. Tocheva,G. Murshudov,V. Alva, & T.A.M. Bharat, Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans, Proc. Natl. Acad. Sci. U.S.A. 120 (16) e2215808120, https://doi.org/10.1073/pnas.2215808120 (2023). Lily Zhao, Cesar A Perez-Fernandez, Jocelyne DiRuggiero, K T Ramesh, Extremophile survives the transient pressures associated with impact-induced ejection from Mars, PNAS Nexus, Volume 5, Issue 3, March 2026, pgag018, https://doi.org/10.1093/pnasnexus/pga... Daly MJ. The scientific revolution that unraveled the astonishing DNA repair capacity of the Deinococcaceae: 40 years on. Can J Microbiol. 2023;69(10):369-386. doi:10.1139/cjm-2023-0059 Feng Liu, Nuomin Li, Yongqian Zhang, The radioresistant and survival mechanisms of Deinococcus radiodurans, Radiation Medicine and Protection, Volume 4, Issue 2, 2023, Pages 70-79, ISSN 2666-5557, https://doi.org/10.1016/j.radmp.2023..... Daly MJ, Gaidamakova EK, Matrosova VY, Kiang JG, Fukumoto R, Lee D-Y, et al. (2010) Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans. PLoS ONE 5(9): e12570. https://doi.org/10.1371/journal.pone.... Join this channel to get access to perks:    / @clockworkbio