Advanced Therapies for Crohn Disease: Biologics and JAK Inhibitors | Clinical Capsules Podcast

New guidelines for moderate to severe Crohn disease help streamline more advanced therapy options, such as biologics and JAK inhibitors. In this episode, TRC Healthcare Assistant Editor and Clinical Pharmacist Gina Corley, PharmD, walks through the latest guideline updates for moderate to severe Crohn disease. She breaks down advanced therapy options such as biologics and JAK inhibitors, discusses how factors like prior biologic exposure shape treatment decisions, and where immunomodulators and steroids fit in. This is an excerpt from our March 2026 Pharmacy Essential Updates continuing education webinar series. 🏷️Use code cc1026 at checkout for 10% off a new or upgraded subscription. https://trchealthcare.com/shop/?trc_p... ****** CE Information: TRC Healthcare offers CE credit for this podcast for pharmacist subscribers at our platinum level or higher and pharmacy technician subscribers. Log in to your Pharmacist’s Letter or Pharmacy Technician’s Letter account and look for the title of this podcast in the list of available CE courses. https://trchealthcare.com/login/ None of the speakers have anything to disclose. Claim Credit: https://learning.therapeuticresearch.... ****** Clinical Resources from Pharmacist’s Letter, Pharmacy Technician’s Letter, and Prescriber Insights: Article: Prioritize Advanced Therapies in Crohn Disease: https://learning.therapeuticresearch.... Chart: Biologics and JAK Inhibitors for Moderate to Severe Crohn Disease: https://learning.therapeuticresearch.... Don’t miss out! Subscribe today to stay ahead with trusted insights and tools: 🎓 Are you a student? Great news—students can access a free version of Pharmacist’s Letter. https://login.therapeuticresearch.com... 📌 If you’re not yet a subscriber, find out more about our product offerings at trchealthcare.com. Connect with us: 🗪 Send us a Fan Mail: https://www.buzzsprout.com/2442384/fa... 👍 Follow, rate, and review this show in your favorite podcast app. 📩 You can also reach out to provide feedback or make suggestions by emailing us at [email protected]. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. 00:00 - Introduction 00:34 - CE Information 01:07 - What is Crohn Disease? 02:15 - Evolution of Treatment Guidelines 03:55 - Understanding Biologics & Advanced Therapies 06:21 - TNF-Alpha Inhibitors & Dosing Details 08:25 - Interleukin & Anti-Integrin Therapies 11:15 - Oral Treatment: JAK Inhibitor (Upadacitinib) 12:04 - Patient Risks, Side Effects & Vaccines 13:08 - Pharmacy Practice Pearls & Storage 14:32 - Conclusion