Is Life Purposeful? A Paradigm Shift in Understanding Living Systems | Denis Noble & Raymond Noble

Denis Noble is Emeritus Professor and co-Director of Computational Physiology who held the Burdon Sanderson Chair of Cardiovascular Physiology at the University of Oxford. He is one of the pioneers of systems biology and developed the first viable mathematical model of the working heart. He is also a philosopher of biology, and his books The Music of Life and Dance to the Tune of Life challenge the foundations of current biological sciences, question the central dogma, its unidirectional view of information flow, and its imposition of a bottom-up methodology for research in the life sciences. Raymond Noble is Honorary Associate Professor at the Institute for Women’s Health, University College London. He held a Rockefeller Senior Research Fellowship with a joint appointment in Physiology and Obstetrics and Gynaecology at University College London, where he became Deputy Dean of Life Sciences and Graduate Tutor in Women’s Health and where he also taught medical ethics in reproductive health. He is a Fellow of the Royal Society of Biology and a chartered biologist, writing extensively on biological theory and philosophy, working extensively on how organisms sense their environment and make choices. Denis & Ray are brothers and co-authors of the book: "Understanding Living Systems" (2023). It describes life is definitively purposive and creative. Organisms use genes in controlling their destiny. This book presents a paradigm shift in understanding living systems. The genome is not a code, blueprint or set of instructions. It is a tool orchestrated by the system. This book shows that gene-centrism misrepresents what genes are and how they are used by living systems. It demonstrates how organisms make choices, influencing their behaviour, their development and evolution, and act as agents of natural selection. It presents a novel approach to fundamental philosophical and cultural issues, such as free-will. Reading this book will make you see life in a new light, as a marvellous phenomenon, and in some sense a triumph of evolution. We are not in our genes, our genes are in us. TIMESTAMPS: 0:00 - Introduction 2:45 - Consciousness & the Mind-Body Dichotomy 12:50 - Biology's Evolution & the Importance of Stochasticity 18:00 - The Gene Delusion 25:35 - Arguments Against Richard Dawkins' "Selfish Gene" 35:45 - Moral/Philosophical Implications of The Selfish Gene 39:19 - Purposive Explanations of Life & Understanding Living Systems 45:40 - Ecological Intelligence 56:05 - Consciousness & the Self 1:05:07 - Biological Evolution from a Physiological Perspective 1:21:18 - The Music of Life (Unselfish Gene) 1:29:00 - Free Will & Dogma 1:36:03 - The Story of Noble Brothers (Differences & Similarities) 1:42:24 - When Two Became One 1:50:45 - Teleology & The Purpose of Life (Final Thoughts) 1:56:40 - Conclusion EPISODE LINKS: Denis: https://tinyurl.com/7uzjuxxm Ray: https://tinyurl.com/25z9jnk5 Books: https://tinyurl.com/bdcpwetj Denis' Publications: https://tinyurl.com/yr3es4ht Ray's Publications: https://tinyurl.com/yunnfjc5 CONNECT: Podcast: https://creators.spotify.com/pod/show... Website: https://tevinnaidu.com X:   / drtevinnaidu   Facebook:   / drtevinnaidu   Instagram:   / drtevinnaidu   LinkedIn:   / drtevinnaidu   ============================= Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields. #DenisNoble #RaymondNoble #Evolution #Life #Purpose