INTOLERÂNCIA ao Álcool? (Deficiência de Aldeído Desidrogenase - ALDH2) | COMIDA Lab // PratoFundo
➤ #PF10years: Have you ever heard of Alcohol Intolerance or Aldehyde Dehydrogenase 2 Deficiency? No? We'll explain everything! It's the cause of the famous Asian Glow, Asian Flush, Alcohol flush reaction, or Alcohol Redness Reaction. ▶︎ FULL ARTICLE: http://pratofundo.com/4871/ ▶︎ Lactose Intolerance: • 5 Fatos sobre INTOLERÂNCIA À LACTOSE | Pra... ▶︎ LIKED IT? Give the video a LIKE! Is it edible? ;) ▶︎ For fresh videos, SUBSCRIBE to the channel: http://prfd.net/assine/ LET'S TALK! Website: http://pratofundo.com/ Instagram: / pratofundo Facebook: / pratofundo Twitter: / pratofundo Google+: http://google.com/+PratoFundoPlus/ Snapchat: dishfundo BIBLIOGRAPHY BROOKS, P. J. et al. The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption. PLoS Medicine, vol. 6, no. 3, Mar. 2009. CHEN, C.-H. et al. Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities. Physiological Reviews, vol. 94, no. 1, p. 1–34, Jan. 2014. ENG, M. Y.; LUCZAK, S. E.; WALL, T. L. ALDH2, ADH1B, and ADH1C genotypes in Asians: a literature review. Alcohol Research & Health: The Journal of the National Institute on Alcohol Abuse and Alcoholism, vol. 30, no. 1, p. 22–27, 2007. ENOMOTO, N.; TAKADA, A.; DATE, T. Genotyping of the aldehyde dehydrogenase 2 (ALDH2) gene using the polymerase chain reaction: evidence for single point mutation in the ALDH2 gene of ALDH2-deficiency. Gastroenterologia Japonica, v. 26, no. 4, p. 440–447, Aug. 1991. IARC. International Agency for Research on Cancer. Agents classified by the IARC monographs, v. 1–117, 2016. LEHNINGER, Albert L.; NELSON, David L.; COX, Michael M. Lehninger Principles of Biochemistry. New York: W. H. Freeman and Company, 2007. MATSUO, K. et al. The aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism interacts with alcohol drinking in the risk of stomach cancer. Carcinogenesis, vol. 34, no. 7, p. 1510–1515, Jul. 2013. McGEE, Harold. On food and cooking: the science and lore of the kitchen. New York: Scribner, 2004. (Portuguese | English) NCBI: Gene. ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) [Homo sapiens (human)] – Gene – NCBI. Available at: https://www.ncbi.nlm.nih.gov/gene/217. Accessed on: 23 Jan. 2017. Overview: How Is Alcohol Metabolized by the Body? NIAAA Publications. Available at: https://pubs.niaaa.nih.gov/publicatio.... Accessed on: 24 Jan. 2017. PENG, G.-S.; YIN, S.-J. Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations. Human Genomics, vol. 3, no. 2, p. 121–127, 1 Jan. 2009. TOMITA, Y. et al. Effects of chronic ethanol intoxication on aldehyde dehydrogenase in mouse liver. Alcohol and Alcoholism (Oxford, Oxfordshire), v. 27, no. 2, p. 171–180, mar. 1992. WANG, X. et al. Heterotetramers of human liver mitochondrial (class 2) aldehyde dehydrogenase expressed in Escherichia coli: a model to study the heterotetramers expected to be found in oriental people. Journal of Biological Chemistry, v. 271, n. 49, p. 31172–31178, Dec. 6, 1996. PHOTOS: Mitochondria: University of Wisconsin Madison 3D Structure Alcohol Dehydrogenase: EMW, https://goo.gl/XHNNGH 3D Structure Aldehyde Dehydrogenase: EMW, https://goo.gl/acitoq SOUNDTRACK "Funkorama", "Ouroboros", "Local Forecast" and "Wallpaper" by Kevin MacLeod (incompetech.com). Licensed under Creative Commons Attribution: (https://creativecommons.org/licenses/...) Source: http://incompetech.com/music/royalty-... Source: http://incompetech.com/music/royalty-... Source: http://incompetech.com/music/royalty-... Music: YouTube Library.

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