Diagnosing EGPA: Recognizing Signs and Symptoms of the Disease

Eosinophilic granulomatosis with polyangiitis (EGPA) is one of the rarest forms of vasculitis with primary manifestations of moderate-to-severe asthma and peripheral eosinophilia. While early diagnosis can prevent cumulative organ damage, lack of disease awareness and overlap of symptoms with other common conditions often results in delayed recognition of EGPA. Earlier diagnosis can prevent the cumulative organ damage that results from vascular inflammation and eosinophil-dense tissue deposits associated with EGPA. Identification of EGPA requires a high index of suspicion, and conditions with features of eosinophilia and vasculitis need to be ruled out before a diagnosis of EGPA is confirmed. The diagnosis of EGPA relies primarily on the presence of clinical characteristics, as no highly specific or sensitive validated diagnostic tests for EGPA currently exist. During this 30-minute CMEO Snack, Drs. Wechsler and Dua will identify best practices and current guidelines for the clinical evaluation and differential diagnosis of EGPA. Using a case presentation to frame the discussion, faculty will explain the differential diagnosis of EGPA as well as how to integrate diagnostic methods and interpret results. Learn More and Claim Credit: https://www.cmeoutfitters.com/activit...