DLS: Jürgen Popp - Translational Biophotonics. From Ideas to Instruments

The use of optical approaches outside specialized laboratories directly at the end user requires easy to use optical instruments with a high TRL. Here, the application of spectroscopic methods to address biomedical research has grown over the past years and has advanced into a new era due to advances in instrumentation and most importantly due to an enhanced cross-disciplinary dialogue between spectroscopists and end-user like e.g. clinicians. In this contribution we report on various innovative technological concepts for bringing optical approaches closer to the end-user like e.g. clinical use. We will focus on molecular-sensitive spectroscopic methods, with particular emphasis on Raman spectroscopy and their combination with other spectroscopic / optical modalities, to provide a multimodal approach. We will start with novel multimodal spectroscopic instrumentation (like e.g. innovative Raman fiber probes, clinically usable multimodal microscopes or endospectroscopic probes etc.) for precise surgical guidance and intraoperative histopathological examination of tissue under in-vivo or near in-vivo conditions. Furthermore, we report on a high-throughput Raman spectroscopy platform for the analysis of cells. With this platform Raman spectra of tens of thousands of cells can be rapidly measured via a complete automation of the complete process chain. At the end we introduce an automated Raman platform in combination with specially developed chips (e.g. dielectrophoresis chip) for microbial analysis. The application of this approach in a clinical environment for a rapid identification of sepsis pathogens together with an antibiotic susceptibility testing will be presented. The Distinguished Lecturer Series brings leading minds from all areas relevant to the science of light to MPL in Erlangen. It presents the unique opportunity for scientific exchange with the speakers to a broad audience. The topics range from terahertz optics with graphene, over self-organising proteins to particle accelerators on a chip. One special highlight will be the talk of the Canadian optical physicist Donna Strickland, Nobel laureate of 2018. All lectures will start at 15.00 CET and will be transmitted via stream. If you would like to attend, please register here for our DLS newsletter: https://mpl.mpg.de/newsletter/​ You will then receive the link for the zoom conference by e-mail shortly before the presentation. Click here for an overview of all the lectures: https://mpl.mpg.de/news-events/dls/​ #Photonics #Biophotonics #dlsMPL #DistinguishedLecturerSeries