Antibody Discovery: Functional Assay Data Integration

This video guide demonstrates how to import and integrate functional assay data (e.g., ELISA, SPR) with your high-throughput NGS antibody sequences on Platforma. We walk you through configuring the Immune Assay Data block to annotate your clonotypes with functional metrics, enabling you to filter, visualize, and select the most promising antibody candidates. In this video, you will learn how to: Associate functional assay data with antibody clonotypes from NGS. Configure key matching parameters, including the sequence region and similarity thresholds. Use different alignment scores like BLOSUM for biochemically aware matching. Interpret the matching results to see how many clonotypes correspond to your functional hits. Visualize annotated "hit" data in the Clonotype Browser and Clonotype Space UMAPs. Platforma is a no-code, end-to-end bioinformatics platform designed to empower biologists and immunologists to get from raw data to publication-ready discoveries without coding expertise. ➡️ Explore Platforma for antibody discovery: https://platforma.bio ➡️ Read our Documentation on Antibody Discovery: https://docs.platforma.bio/guides/ant...