Losartana com Anlodipino: Pode Tomar no Mesmo Horário? (Cirurgião Vascular Explica TUDO)

Do you take losartan and amlodipine together and have questions about the right time to take them, the risks, and the mistakes that can sabotage your treatment? In this video, I explain EVERYTHING you need to know! 👇 In this video, I, Dr. Antonio Cascelli, vascular surgeon and angiologist, explain clearly and definitively how losartan and amlodipine work in your body, why they were designed to work together, the best time to take them (together or separately?), the 5 most common and dangerous mistakes people make, and what you should NEVER do while using this combination. If you have hypertension and take these medications, this video can change the way you manage your blood pressure! 📚 KEEP LEARNING WITH US! (Books, Anti-Thrombosis Protocol, E-books and much more) ➡ https://antoniocascelli.com/vitrine/ 💎 BECOME A CHANNEL MEMBER AND UNLOCK EXCLUSIVE BENEFITS: (Courses, scripts, articles, recipes and much more!) ➡    / @drantoniocascelli   🤝 SUPPORT OUR SOCIAL PROJECTS (Antonio Cascelli Institute) PIX - CNPJ: 62.721.364/0001-18 ⏳ VIDEO CHAPTERS: 00:00 - Can you take losartan and amlodipine together? 01:30 - How high blood pressure works (the squeezed hose) 02:30 - How losartan works (hormonal blockade) 03:45 - How amlodipine works (muscle relaxation) 05:00 - Why the two together are superior 06:00 - What is the best time to take it? 07:15 - Mistake 1: Stopping when blood pressure normalizes 07:45 - Mistake 2: Grapefruit juice (DANGER!) 08:15 - Mistake 3: Anti-inflammatories that sabotage 08:45 - Mistake 4: Excess potassium 09:15 - Mistake 5: Ignoring swelling in the ankles 10:00 - What to NEVER do with this combination 10:45 - My final recommendation 🔬 SCIENTIFIC INFORMATION CITED IN THIS VIDEO: (Studies based on international cardiology and surgery guidelines) (vascular) ➡ LIFE Trial (The Lancet): A study with over 9,000 hypertensive patients demonstrated that losartan reduced the risk of stroke by 25% compared to atenolol, with a superior safety profile. ➡ ACCOMPLISH Trial (The Lancet): A study with 11,506 high-risk hypertensive patients showed that the combination of angiotensin blocker + amlodipine reduced cardiovascular events by 20% more than the combination with a diuretic. ➡ Mechanism of Amlodipine (JACC): Blockade of L-type calcium channels in vascular smooth muscle cells promotes sustained vasodilation for more than 24 hours with a once-daily dose. ➡ Interaction with Grapefruit: Inhibition of the hepatic and intestinal CYP3A4 enzyme by the furanocoumarin present in grapefruit increases the bioavailability of amlodipine by up to 60%. 🔔 DON'T FORGET TO: 👍 Like the video! 📝 Subscribe to the channel so you don't miss any content:    / @drantoniocascelli   💬 Leave a comment: Do you take losartan and amlodipine? Do you take them together or separately? What time? ⚠️ LEGAL NOTICE: The information contained in this video is strictly educational and informative. This content does not replace medical consultation, diagnosis, or treatment with your cardiologist or angiologist. Never change doses or stop medication without your doctor's guidance. #Losartan #Amlodipine #HighBloodPressure #Hypertension #DrAntonioCascelli #BloodPressureMedications #VascularHealth #Circulation #HealthyHeart